The North Carolina State University, College of Veterinary Medicine, Center for Chemical Toxicology Research and Pharmacokinetics records contain laboratory and experiment log books of projects and grants related to studies of Isolated Perfused Porcine Skin Flaps (IPPSF). These records also include two pieces of historic equipment used for these experiments: an Osborne computer for the Food Animal Residue Avoidance Databank (FARAD) and a pressure transducer. Materials range in date from 1981 to 2012.
The Center for Chemical Toxicology Research and Pharmacokinetics performs research on the structure and function of skin focused on transdermal drug delivery, cutaneous toxicology, metabolism and pharmacokinetics employing innovative animal models and other pharmacokinetic research. The Center also helps maintain the USDA-supported Food Animal Residue Avoidance Databank (FARAD), a program established to prevent or mitigate illegal or harmful residues of drugs, pesticides, biotoxins and other chemical agents that may contaminate foods of animal origin.
The Cutaneous Pharmacology and Toxicology Center, located in the College of Veterinary Medicine, was chartered by the UNC Board of Governors on March 10, 1989 to "Perform scientific research on the structure and function of skin focused on transdermal drug delivery, cutaneous toxicology, metabolism and pharmacokinetics employing innovative animal models and other pharmacokinetic research." This extensive research led to the creation, establishment and maintenance of the national USDA-supported Food Animal Residue Avoidance Databank (FARAD) in 1981. FARAD was established to prevent or mitigate illegal or harmful residues of drugs, pesticides, biotoxins and other chemical agents that may contaminate foods of animal origin.The Center was renamed the Center for Chemical Toxicology Research and Pharmacokinetics (CCTRP) by UNC President Molly Broad on December 6, 2001 to officially reflect this dual mission. These two formal missions guide the nature of the research performed by the CCTRP and provide the necessary research base to support a rigorous graduate and post-graduate training program in comparative pharmacology, general toxicology and nanotechnology designed to produce health scientists for academia, industry and government.
The Center has been awarded numerous pretigious grants from agencies such as the National Institute of Occupational Safety and Health (NIOSH), the Environmental Protection Agency (EPA), the Agency for Toxic Substances and Disease Registry (ATSDR), and the Department of Defense to conduct experiments on porcine (pig) skin flaps, which have proven to apply to human skin as well. Many of these studies have been carried out by Dr. Jim Riviere, the co-founder and co-director of FARAD and the Director of the Center for Chemical Toxicology Research and Pharmacokinetics.
The North Carolina State University, College of Veterinary Medicine, Center for Chemical Toxicology Research and Pharmacokinetics contain laboratory and experiment log books documenting grants awarded to the Center for studies of Isolated Perfused Porcine Skin Flaps (IPPSF). These records also include two pieces of historic equipment used for these experiments, an Osborne computer for the Food Animal Residue Avoidance Databank (FARAD) and a pressure transducer. Materials range in date from 1981 to 2011.
Materials are arranged by project (that may span several grants). They are mostly chronological.
The NC State University Libraries generally claims only physical ownership of most Special Collections materials. These materials are made available for use in research, teaching, and private study, pursuant to U.S. Copyright law. Libraries staff are unable to advise on copyright and other legal matters; the user assumes full responsibility for any use of the materials, including but not limited to, infringement of copyright and publication rights of reproduced materials. Helpful resources for assessing copyright include Cornell Libraries' "Copyright Services: Copyright Term and the Public Domain" and copyright.gov. This collection may contain materials with sensitive or confidential information about identifiable living individuals, which may be protected under federal or state laws and regulations. Researchers are advised that there may be legal ramifications for disclosing this information.
The University Archives operates in accordance with the State Public Records Act, with unrestricted access to records not covered by state and federal statutes and regulations.
[Identification of item], North Carolina State University, College of Veterinary Medicine, Center for Chemical Toxicology Research and Pharmacokinetics, UA 145.041, Special Collections Research Center, North Carolina State University Libraries, Raleigh, NC
Transferred from the North Carolina State University, College of Veterinary Medicine, Center for Chemical Toxicology Research and Pharmacokinetics.
Processed by: Cathy Dorin-Black, 2013 December; Finding aid written by: Cathy Dorin-Black, 2013 December; Finding aid updated by Gevorg Vardanyan, 2023 September.
Missing 1,2,3,9,11, and 12
Missing 67 and 68
Missing 75,76,77, and 84
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[Identification of item], North Carolina State University, College of Veterinary Medicine, Center for Chemical Toxicology Research and Pharmacokinetics, UA 145.041, Special Collections Research Center, North Carolina State University Libraries, Raleigh, NC
The NC State University Libraries generally claims only physical ownership of most Special Collections materials. These materials are made available for use in research, teaching, and private study, pursuant to U.S. Copyright law. Libraries staff are unable to advise on copyright and other legal matters; the user assumes full responsibility for any use of the materials, including but not limited to, infringement of copyright and publication rights of reproduced materials. Helpful resources for assessing copyright include Cornell Libraries' "Copyright Services: Copyright Term and the Public Domain" and copyright.gov. This collection may contain materials with sensitive or confidential information about identifiable living individuals, which may be protected under federal or state laws and regulations. Researchers are advised that there may be legal ramifications for disclosing this information.
The University Archives operates in accordance with the State Public Records Act, with unrestricted access to records not covered by state and federal statutes and regulations.