Works (12)

Updated: July 5th, 2023 15:56

2012 journal article

Synthesis and Physicochemical Properties of Metallobacteriochlorins

INORGANIC CHEMISTRY, 51(17), 9443–9464.

By: C. Chen n, E. Sun n, D. Fan n, M. Taniguchi n, B. McDowell n, E. Yang*, J. Diers*, D. Bocian*, D. Holten*, J. Lindsey n

Contributors: C. Chen n, E. Sun n, D. Fan n, M. Taniguchi n, B. McDowell n, E. Yang*, J. Diers*, D. Bocian*, D. Holten*, J. Lindsey n

MeSH headings : Absorption; Chemical Phenomena; Chemistry Techniques, Synthetic; Electrochemistry; Electrons; Metalloporphyrins / chemical synthesis; Metalloporphyrins / chemistry; Porphyrins / chemistry
TL;DR: Electrochemical characteristics of (metal-free) bacteriochlorins were probed through electrochemical measurements along with density functional theory calculation of the energies of the frontier molecular orbitals and photophysical properties are generally similar to those of the metal-free analogues. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Expanded Scope of Synthetic Bacteriochlorins via Improved Acid Catalysis Conditions and Diverse Dihydrodipyrrin-Acetals

JOURNAL OF ORGANIC CHEMISTRY, 75(4), 1016–1039.

By: M. Krayer n, M. Ptaszek n, H. Kim n, K. Meneely n, D. Fan n, K. Secor n, J. Lindsey n

MeSH headings : Acetals / chemistry; Acids / chemistry; Catalysis; Crystallography, X-Ray; Metalloporphyrins / chemical synthesis; Metalloporphyrins / chemistry; Models, Molecular; Molecular Structure; Photochemistry; Porphyrins / chemical synthesis; Porphyrins / chemistry; Pyrroles / chemistry; Spectroscopy, Near-Infrared
TL;DR: Four promising acid catalysis conditions are identified and 15 new bacteriochlorins prepared herein exhibit a long-wavelength absorption band in the range 707-759 nm, providing tunable access to the near-infrared region, which expands the scope of available bacterio chlorins for fundamental studies and diverse applications. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

In Vitro Photodynamic Therapy and Quantitative Structure-Activity Relationship Studies with Stable Synthetic Near-Infrared-Absorbing Bacteriochlorin Photosensitizers

JOURNAL OF MEDICINAL CHEMISTRY, 53(10), 4018–4027.

By: Y. Huang, P. Mroz*, T. Zhiyentayev, S. Sharma*, T. Balasubramanian, C. Ruzie*, M. Krayer*, D. Fan* ...

MeSH headings : Cell Death / drug effects; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Infrared Rays; Photochemotherapy; Photosensitizing Agents / chemistry; Photosensitizing Agents / metabolism; Photosensitizing Agents / pharmacology; Porphyrins / chemistry; Porphyrins / metabolism; Porphyrins / pharmacology; Quantitative Structure-Activity Relationship; Quantum Theory
TL;DR: Testing of 12 new stable synthetic bacteriochlorins for PDT activity described, which possess a variety of peripheral substituents and are very potent in killing cancer cells in vitro after illumination, gives them great potential as photosensitizers for treatment of cancer. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Stable synthetic bacteriochlorins overcome the resistance of melanoma to photodynamic therapy

FASEB JOURNAL, 24(9), 3160–3170.

By: P. Mroz*, Y. Huang*, A. Szokalska*, T. Zhiyentayev*, S. Janjua*, A. Nifli*, M. Sherwood*, C. Ruzie n ...

author keywords: multidrug resistance; melanosomes; electron microscopy
MeSH headings : Animals; Cell Line, Tumor; Male; Melanoma / drug therapy; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Molecular Structure; Photochemotherapy / methods; Porphyrins / chemical synthesis; Porphyrins / chemistry; Porphyrins / therapeutic use
TL;DR: The extent of melanin contribution to melanoma resistance to PDT was investigated in a set of melanoma cell lines that markedly differ in the levels of pigmentation;3 new bacteriochlorins successfully overcame the resistance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Chlorin-Bacteriochlorin Energy-transfer Dyads as Prototypes for Near-infrared Molecular Imaging Probes: Controlling Charge-transfer and Fluorescence Properties in Polar Media

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 85(4), 909–920.

MeSH headings : Energy Transfer; Fluorescence; Molecular Probes; Oxidation-Reduction; Porphyrins / chemistry; Quantum Theory; Spectroscopy, Near-Infrared
TL;DR: Controlling the extent of excited‐state quenching in polar media will allow the favorable photophysical properties of the chlorin–bacteriochlorin dyads to be exploited in vivo and facilitate selective excitation/detection and multiprobe applications using both intensity‐ and lifetime‐imaging techniques. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 patent

Methods and intermediates for the synthesis of porphyrins

By: J. Lindsey, M. Taniguchi, A. Balakumar & D. Fan

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Self-assembled photosynthesis-inspired light harvesting material and solar cells containing the same

By: J. Lindsey, M. Chinnasamy & D. Fan

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Examination of chlorin-bacteriochlorin energy-transfer dyads as prototypes for near-infrared molecular imaging probes

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 84(5), 1061–1072.

By: H. Kee*, R. Nothdurft*, C. Muthiah n, J. Diers*, D. Fan n, M. Ptaszek n, D. Bocian*, J. Lindsey n, J. Culver*, D. Holten*

MeSH headings : Dimethyl Sulfoxide / chemistry; Energy Transfer; Fluorescent Dyes / chemistry; Metalloporphyrins / chemical synthesis; Metalloporphyrins / chemistry; Molecular Probes / analysis; Molecular Probes / chemistry; Molecular Structure; Photochemistry; Porphyrins / chemistry; Spectroscopy, Near-Infrared; Stereoisomerism; Toluene / chemistry
TL;DR: The narrow spectral widths enabled excellent selectivity in excitation and detection of one chlorin–bacteriochlorin energy‐transfer dyad in the presence of the other upon diffuse optical tomography of solution‐phase phantoms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Synthesis and excited-state photodynamics of a chlorin-bacteriochlorin dyad-through-space versus through-bond energy transfer in tetrapyrrole arrays

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 84(3), 786–801.

MeSH headings : Computer Simulation; Energy Transfer; Light; Molecular Structure; Photochemistry; Porphyrins / chemical synthesis; Porphyrins / chemistry; Quantum Theory; Tetrapyrroles / chemistry
TL;DR: The energy‐transfer characteristics of FbC‐pe‐FbB are compared with those previously obtained for analogous phenylethyne‐linked dyads consisting of two porphyrins or two oxochlorins, facilitated by density functional theory calculations that elucidate the molecular‐orbital characteristics of the energy donor and acceptor constituents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Regioselective 15-bromination and functionalization of a stable synthetic bacteriochlorin

JOURNAL OF ORGANIC CHEMISTRY, 72(14), 5350–5357.

By: D. Fan n, M. Taniguchi n & J. Lindsey n

Contributors: D. Fan n, M. Taniguchi n & J. Lindsey n

MeSH headings : Bromine / chemistry; Deuterium Exchange Measurement; Magnetic Resonance Spectroscopy; Molecular Structure; Palladium / chemistry; Porphyrins / chemical synthesis; Porphyrins / chemistry; Spectrophotometry; Stereoisomerism
TL;DR: The 15-bromo-5-methoxybacteriochlorin MeO-BC-Br15 was subjected to three types of Pd-mediated coupling reactions to give six bacteriochlorins bearing functional groups at the 15-position, which enables synthetic bacterio chlorins to be tailored for a variety of applications. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2005 journal article

1,9-bis(N,N-dimethylaminomethyl)dipyrromethanes in the synthesis of porphyrins bearing one or two meso substituents

TETRAHEDRON, 61(43), 10291–10302.

By: D. Fan n, M. Taniguchi n, Z. Yao n, S. Dhanalekshmi n & J. Lindsey n

Contributors: D. Fan n, M. Taniguchi n, Z. Yao n, S. Dhanalekshmi n & J. Lindsey n

author keywords: dipyrromethane; aminomethylation; porphyrin; zinc
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2005 journal article

Imine-substituted dipyrromethanes in the synthesis of porphyrins bearing one or two meso substituents

JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 9(8), 554–574.

By: M. Taniguchi n, A. Balakumar n, D. Fan n, B. McDowell n & J. Lindsey n

Contributors: M. Taniguchi n, A. Balakumar n, D. Fan n, B. McDowell n & J. Lindsey n

author keywords: dipyrromethane; pyrrole; imine; Schiff's base; porphyrin; aerobic oxidation; dipyrrin; self-assembly; zinc
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

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