Works (72)

Updated: March 29th, 2024 00:50

2024 journal article

Biomarkers of Metabolic Adaptation to High Dietary Fats in a Mouse Model of Obesity Resistance

METABOLITES, 14(1).

By: F. Milhem n, L. Hamilton n, E. Skates n, M. Wilson n, S. Johanningsmeier n & S. Komarnytsky n

co-author countries: Jordan 🇯🇴 United States of America 🇺🇸
author keywords: body composition; metabolic inflexibility; metabolic rate; dietary fats; skeletal muscle remodeling; glucose tolerance; microbiome
Sources: ORCID, Web Of Science
Added: January 26, 2024

2024 article

Comparative evaluation of the antioxidant and anti-inflammatory potential of fennel essential oil obtained by conventional and supercritical fluid extraction

Tanveer, M., Shehzad, A., Komarnytsky, S., Butt, M. S., Shahid, M., & Aadil, R. M. (2024, February 15). BIOMASS CONVERSION AND BIOREFINERY, Vol. 2.

co-author countries: France 🇫🇷 Pakistan 🇵🇰 United States of America 🇺🇸
author keywords: Soxhlet extraction; Supercritical fluid extraction; Antioxidant Assays; Pakistani fennel; Egyptian fennel
Sources: Web Of Science, ORCID
Added: March 4, 2024

2024 journal article

Functional recovery following traumatic brain injury in rats is enhanced by oral supplementation with bovine thymus extract

FASEB JOURNAL, 38(3).

By: N. Surzenko*, J. Bastidas*, R. Reid*, J. Curaba*, W. Zhang*, H. Bostan*, M. Wilson*, A. Dominique* ...

co-author countries: United States of America 🇺🇸
author keywords: autoantibodies; autophagy; glandular therapy; nutrition; oral tolerance; phagocytosis; RNA-Seq
Sources: Web Of Science, ORCID
Added: February 19, 2024

2024 journal article

Obesity-Resistant Mice on a High-Fat Diet Display a Distinct Phenotype Linked to Enhanced Lipid Metabolism

NUTRIENTS, 16(1).

By: F. Milhem n, E. Skates*, M. Wilson* & S. Komarnytsky n

co-author countries: Jordan 🇯🇴 United States of America 🇺🇸
author keywords: dietary fats; energy substrate; body composition; metabolic rate; individual variability; personalized nutrition
Sources: Web Of Science, ORCID
Added: January 22, 2024

2023 journal article

Alleviation of Pain, PAIN Interference, and Oxidative Stress by a Novel Combination of Hemp Oil, Calamari Oil, and Broccoli: A Randomized, Double-Blind, Placebo-Controlled Trial

NUTRIENTS, 15(12).

By: C. Carlisle*, K. Polley*, C. Panda*, K. Barron*, M. Hamrock*, A. Dominique*, B. Metzger*, S. Le Brun-Blashka*, S. Komarnytsky n

co-author countries: United States of America 🇺🇸
author keywords: whole food; botanical; dietary supplement; bioactive components; antioxidants; hemp oil; pain management; nutrition
MeSH headings : Adult; Humans; Middle Aged; Aged; Fatty Acids, Omega-3; Leukocytes, Mononuclear; Brassica; Chronic Pain / drug therapy; Reactive Oxygen Species / pharmacology; Dietary Supplements; Oxidative Stress; Double-Blind Method
Sources: Web Of Science, ORCID
Added: July 10, 2023

2023 article

Berries in Microbiome-Mediated Gastrointestinal, Metabolic, and Immune Health

Komarnytsky, S., Wagner, C., Gutierrez, J., & Shaw, O. M. (2023, February 4). CURRENT NUTRITION REPORTS, Vol. 2.

By: S. Komarnytsky n, C. Wagner n, J. Gutierrez n & O. Shaw*

co-author countries: New Zealand 🇳🇿 United States of America 🇺🇸
author keywords: Gut microbiota; Immune modulation; Chronic inflammation; Metabolic syndrome; Dietary fiber; Phenolic metabolites; Clinical study
MeSH headings : Humans; Fruit / metabolism; Microbiota; Polyphenols / metabolism; Gastrointestinal Tract; Gastrointestinal Microbiome
Sources: ORCID, Web Of Science
Added: February 5, 2023

2023 review

Current Status and Nutritional Value of Green Leaf Protein

[Review of ]. NUTRIENTS, 15(6).

By: C. Balfany n, J. Gutierrez*, M. Moncada n & S. Komarnytsky n

co-author countries: United States of America 🇺🇸
author keywords: green biomass; plant leaves; alternative proteins; amino acid; functionality; complete protein; nutritional value; leaf protein concentrate
MeSH headings : Plant Leaves / chemistry; Crops, Agricultural; Nutritive Value; Plant Proteins / metabolism; Minerals / analysis
Sources: ORCID, Web Of Science
Added: March 9, 2023

2023 review

Essential Minerals and Metabolic Adaptation of Immune Cells

[Review of ]. NUTRIENTS, 15(1).

By: M. Alghamdi n, J. Gutierrez n & S. Komarnytsky n

co-author countries: United States of America 🇺🇸
author keywords: micronutrient; malnutrition; macrophage polarization; intestinal immunity; mucosal integrity; dietary intervention
MeSH headings : Humans; Cytokines; Minerals; Inflammation; Chemokines; Complement System Proteins; Trace Elements
Sources: Web Of Science, ORCID
Added: December 29, 2022

2023 journal article

Guided Metabolic Detoxification Program Supports Phase II Detoxification Enzymes and Antioxidant Balance in Healthy Participants

NUTRIENTS, 15(9).

By: C. Panda*, S. Komarnytsky n, M. Fleming*, C. Marsh*, K. Barron*, S. Le Brun-Blashka*, B. Metzger*

co-author countries: United States of America 🇺🇸
author keywords: whole food; botanical; detoxification program; liver; antioxidants; free radicals; hepatic markers; GST; SOD; GSH; GSSG ratio
Sources: Web Of Science, ORCID
Added: May 30, 2023

2023 review

Progression to Obesity: Variations in Patterns of Metabolic Fluxes, Fat Accumulation, and Gastrointestinal Responses

[Review of ]. METABOLITES, 13(9).

By: F. Milhem n & S. Komarnytsky n

co-author countries: Jordan 🇯🇴 United States of America 🇺🇸
author keywords: dietary obesity; weight gain; high-fat diet; lipid oxidation; metabolic inflexibility; metabolic rate; obesity-prone; obesity-resistant
Sources: Web Of Science, ORCID
Added: November 27, 2023

2023 journal article

Total Utilization-Upcycling of Mushroom Protein By-Product: Characterization and Assessment as an Alternative Batter Ingredient for Fried Shrimp

FOODS, 12(4).

By: D. Garcia n, S. You n, R. Aleman*, J. King*, S. Komarnytsky n, R. Hoskin n, M. Moncada n

co-author countries: United States of America 🇺🇸
author keywords: repurposing; waste; food ingredients; sustainability; value-added
Sources: ORCID, Web Of Science
Added: February 11, 2023

2022 review

All Polyphenols Are Not Created Equal: Exploring the Diversity of Phenolic Metabolites

[Review of ]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70(7), 2077–2091.

By: C. Vong n, T. Rathinasabapathy n, M. Moncada n & S. Komarnytsky n

co-author countries: United States of America 🇺🇸

Contributors: C. Vong n, T. Rathinasabapathy n, M. Moncada n & S. Komarnytsky n

author keywords: (poly)phenols; phenolic acids; microbiome; microbial catabolism; methylation
MeSH headings : Antioxidants; Flavonoids / metabolism; Humans; Phenols / chemistry; Polyphenols / metabolism; Tannins
Sources: ORCID, Web Of Science
Added: February 12, 2022

2022 journal article

Effect of Wild Blueberry Metabolites on Biomarkers of Gastrointestinal and Immune Health In Vitro

Immuno, 2(2), 293–306.

By: T. Rathinasabapathy n, J. Lomax n, K. Srikanth*, D. Esposito n, C. Kay n & S. Komarnytsky n

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: March 30, 2022

2022 review

Gains and Losses of Agricultural Food Production: Implications for the Twenty-First Century

[Review of ]. ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, 13, 239–261.

By: S. Komarnytsky n, S. Retchin*, C. Vong n & M. Lila n

co-author countries: United States of America 🇺🇸
author keywords: agricultural food systems; genetic improvement; biofortification; phytochemicals; alternative proteins; sustainable agriculture
MeSH headings : Agriculture; Animals; Biodiversity; Climate Change; Crops, Agricultural; Food Supply
Sources: Web Of Science, ORCID
Added: May 23, 2022

2022 article

Mushrooms as Functional and Nutritious Food Ingredients for Multiple Applications

You, S. W., Hoskin, R. T., Komarnytsky, S., & Moncada, M. (2022, June 8). ACS FOOD SCIENCE & TECHNOLOGY, Vol. 6.

By: S. You n, R. Hoskin n, S. Komarnytsky n & M. Moncada n

co-author countries: United States of America 🇺🇸
author keywords: food formulation; novel ingredients; nutrition; functionality
Sources: Web Of Science, ORCID
Added: June 9, 2022

2022 review

Plant-Based Support of Respiratory Health during Viral Outbreaks

[Review of ]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70(7), 2064–2076.

By: T. Rathinasabapathy n, L. Sakthivel* & S. Komarnytsky n

co-author countries: India 🇮🇳 United States of America 🇺🇸

Contributors: T. Rathinasabapathy n, L. Sakthivel* & S. Komarnytsky n

author keywords: licorice; coneflower; ginger; mullein; horehound; elderberry; nettle; antiviral; anti-inflammatory; expectorant; COVID-19
MeSH headings : Disease Outbreaks; Humans; Phytotherapy; Plant Extracts / pharmacology; Respiratory System; Virus Diseases / drug therapy
Sources: ORCID, Web Of Science
Added: February 12, 2022

2021 review

Endocannabinoid System and Its Regulation by Polyunsaturated Fatty Acids and Full Spectrum Hemp Oils

[Review of ]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(11).

By: S. Komarnytsky n, T. Rathinasabapathy n, C. Wagner n, B. Metzger*, C. Carlisle*, C. Panda*, S. Le Brun-Blashka*, J. Troup*, S. Varadharaj*

co-author countries: United States of America 🇺🇸

Contributors: S. Komarnytsky n, T. Rathinasabapathy n, C. Wagner n, B. Metzger*, C. Carlisle*, C. Panda*, S. Le Brun-Blashka*, J. Troup*, S. Varadharaj*

author keywords: ECS tone; phytocannabinoids; inflammation resolution; oxidative stress; systemic redox balance
MeSH headings : Adenosine / metabolism; Animals; Cannabinoids / metabolism; Cannabis / metabolism; Diet; Endocannabinoids / metabolism; Fatty Acids, Unsaturated / metabolism; Homeostasis / physiology; Humans; Inflammation / metabolism; Lipid Metabolism / physiology; Oxidative Stress / physiology; Plant Extracts / metabolism; Signal Transduction / physiology; TRPV Cation Channels / metabolism
Sources: ORCID, Web Of Science
Added: May 24, 2021

2021 journal article

Immune Responses Are Differentially Regulated by Root, Stem, Leaf, and Flower Extracts of Female and Male CBD Hemp (Cannabis sativa L.) Plants

Immuno.

By: L. Esposito*, E. Overbaugh n, J. Xiong n, T. Rathinasabapathy n, S. Komarnytsky n, D. Silva*, D. Esposito n

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸
Source: ORCID
Added: October 26, 2021

2021 journal article

Modulation of Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway by Culinary Sage (Salvia officinalis L.)

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(14).

By: N. Chiang*, S. Ray*, J. Lomax n, S. Goertzen n, S. Komarnytsky n, C. Ho*, J. Munafo*

co-author countries: United States of America 🇺🇸
author keywords: culinary sage; cognition and memory function; brain-derived neurotrophic factor (BDNF); sage extract; benzyl 6-O-beta-D-apiofuranosyl-beta-D-glucoside (B6AG)
MeSH headings : Animals; Brain-Derived Neurotrophic Factor / genetics; Brain-Derived Neurotrophic Factor / metabolism; Cell Line, Tumor; Chromatography, High Pressure Liquid; Gene Expression Regulation, Neoplastic / drug effects; Gene Expression Regulation, Neoplastic / genetics; Glioma / genetics; Glioma / metabolism; Mass Spectrometry; Plant Leaves / chemistry; Rats; Salvia officinalis / chemistry; Signal Transduction / drug effects; Signal Transduction / genetics
Sources: ORCID, Web Of Science
Added: July 10, 2021

2021 journal article

Rheum rhaponticum Root Extract Improves Vasomotor Menopausal Symptoms and Estrogen-Regulated Targets in Ovariectomized Rat Model

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(3).

By: M. Wilson n, V. Konda*, K. Heidt n, T. Rathinasabapathy n, A. Desai* & S. Komarnytsky n

co-author countries: United States of America 🇺🇸

Contributors: M. Wilson n, V. Konda*, K. Heidt n, T. Rathinasabapathy n, A. Desai* & S. Komarnytsky n

author keywords: postmenopausal; estrogens; hot flashes; HRT; ERr 731
MeSH headings : Animals; Biomarkers; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogen Receptor alpha / metabolism; Estrogen Receptor beta / metabolism; Hot Flashes; Menopause / drug effects; Molecular Structure; Ovariectomy; Phytoestrogens / chemistry; Phytoestrogens / pharmacology; Plant Extracts / chemistry; Plant Extracts / pharmacology; Plant Roots / chemistry; Postmenopause; Rats; Rheum / chemistry; Vasomotor System / drug effects
Sources: ORCID, Web Of Science
Added: January 21, 2021

2020 review

Celtic Provenance in Traditional Herbal Medicine of Medieval Wales and Classical Antiquity

[Review of ]. FRONTIERS IN PHARMACOLOGY, 11.

By: C. Wagner n, J. De Gezelle n & S. Komarnytsky n

co-author countries: United States of America 🇺🇸
author keywords: medicinal plants; ethnopharmacology; ethnobotany; herbal texts; bioactive compounds
Sources: Web Of Science, ORCID
Added: April 27, 2020

2020 journal article

Enhanced stability of berry pomace polyphenols delivered in protein-polyphenol aggregate particles to an in vitro gastrointestinal digestion model

Food Chemistry, 331, 127279.

By: J. Xiong n, Y. Chan n, T. Rathinasabapathy n, M. Grace n, S. Komarnytsky n & M. Lila n

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸

Contributors: J. Xiong n, Y. Chan n, T. Rathinasabapathy n, M. Grace n, S. Komarnytsky n & M. Lila n

author keywords: Food matrix; By-product; Stability; Antioxidant; Anti-inflammatory
MeSH headings : Animals; Anthocyanins / analysis; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Antioxidants / analysis; Blueberry Plants / chemistry; Digestion; Food-Processing Industry; Fruit / chemistry; Mice; Plant Extracts / chemistry; Plant Extracts / pharmacokinetics; Plant Proteins, Dietary / chemistry; Polyphenols / pharmacokinetics; Proanthocyanidins / analysis; RAW 264.7 Cells; Vitis / chemistry
Source: ORCID
Added: June 19, 2020

2020 journal article

Exploring the Anti-Acne Potential of Impepho [Helichrysum odoratissimum (L.) Sweet] to Combat Cutibacterium acnes Virulence

FRONTIERS IN PHARMACOLOGY, 10.

By: M. De Canha*, S. Komarnytsky n, L. Langhansova* & N. Lall*

co-author countries: Czechia 🇨🇿 India 🇮🇳 United States of America 🇺🇸 South Africa 🇿🇦
author keywords: Helichrysum odoratissimum (L; ) Sweet; Cutibacterium acnes; anti-acne; antibiofilm; pathogenesis
Sources: Web Of Science, ORCID
Added: March 10, 2020

2020 journal article

Spicing up gastrointestinal health with dietary essential oils

Phytochemistry Reviews, 19(2), 243–263.

co-author countries: Pakistan 🇵🇰 United States of America 🇺🇸

Contributors: M. Tanveer n, C. Wagner n, M. Haq*, N. Ribeiro n, T. Rathinasabapathy n, M. Butt*, A. Shehzad*, S. Komarnytsky n

author keywords: Essential oils; Indigestion; Gastroesophageal reflux; Dyspepsia; Gastritis
Source: ORCID
Added: March 5, 2020

2020 review

The Enigma of Bioactivity and Toxicity of Botanical Oils for Skin Care

[Review of ]. FRONTIERS IN PHARMACOLOGY, 11.

By: E. Moore n, C. Wagner n & S. Komarnytsky n

co-author countries: United States of America 🇺🇸
author keywords: natural oils; skin barrier function; skin aging; wound healing; atopic dermatitis; for skin care
Sources: Web Of Science, ORCID
Added: July 13, 2020

2019 journal article

Alaskan Berry Extracts Promote Dermal Wound Repair Through Modulation of Bioenergetics and Integrin Signaling

FRONTIERS IN PHARMACOLOGY, 10(SEP).

By: D. Esposito n, J. Overall n, M. Grace n, S. Komarnytsky n & M. Lila n

co-author countries: United States of America 🇺🇸

Contributors: D. Esposito n, J. Overall n, M. Grace n, S. Komarnytsky n & M. Lila n

author keywords: skin regeneration; wound healing; Alaskan berries; integrins; proanthocyanidins; epicatechins
Sources: Web Of Science, ORCID
Added: October 14, 2019

2019 journal article

Phenylpropanoid Glycerol Glucosides Attenuate Glucose Production in Hepatocytes

ACS OMEGA, 4(6), 10670–10676.

By: A. Murray*, K. Palatini n, S. Komarnytsky n, T. Gianfagna* & J. Munafo*

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: July 22, 2019

2018 journal article

Berries containing anthocyanins with enhanced methylation profiles are more effective at ameliorating high fat diet-induced metabolic damage

FOOD AND CHEMICAL TOXICOLOGY, 111, 445–453.

By: E. Skates n, J. Overall n, K. DeZego n, M. Wilson n, D. Esposito n, M. Lila n, S. Komarnytsky n

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Bioactive food components; Polyphenols; Obesity; Diabetes; Bioenergetics; Functional food
MeSH headings : Animal Feed; Animals; Anthocyanins / chemistry; Diet; Diet, High-Fat / adverse effects; Energy Metabolism; Fruit / chemistry; Lipid Metabolism; Male; Metabolic Diseases; Methylation; Mice; Mice, Inbred C57BL; Rubus / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Botanical Provenance of Traditional Medicines From Carpathian Mountains at the Ukrainian-Polish Border

FRONTIERS IN PHARMACOLOGY, 9.

By: W. Kozlowska*, C. Wagner n, E. Moore n, A. Matkowski* & S. Komarnytsky n

co-author countries: Poland 🇵🇱 United States of America 🇺🇸
author keywords: ethnobotany; traditional knowledge; herbal texts; bioactive compounds; functional foods; folk remedies
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Anthocyanins in metabolic health and disease

Nutrigenomics and Proteomics in Health and Disease: towards a Systems-Level Understanding of Gene-Diet Interactions, 2nd Edition, 92–124.

By: J. Overall, M. Lila & S. Komarnytsky

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Antibacterial activity of medicinal plants from The Physicians of Myddvai, a 14th century Welsh medical manuscript

JOURNAL OF ETHNOPHARMACOLOGY, 203, 171–181.

By: C. Wagner n, J. De Gezelle n, M. Robertson, K. Robertson, M. Wilson n & S. Komarnytsky n

co-author countries: United States of America 🇺🇸
author keywords: Traditional use; ethnobotany; medicinal plants; microbial infections; antibiotics
MeSH headings : Anti-Bacterial Agents / history; Anti-Bacterial Agents / isolation & purification; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Bacterial Infections / drug therapy; Bacterial Infections / history; Ethnobotany / history; Ethnopharmacology / history; History, Medieval; Humans; Medicine, Traditional / history; Phytotherapy / history; Phytotherapy / methods; Plant Preparations / history; Plant Preparations / pharmacology; Plants, Medicinal / chemistry; Scotland
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Health modifying regions in the oat (Avena sativa) genome responsible for beneficial effects on immune and gastrointestinal health

FASEB Journal, 31.

By: W. Bussler, K. Dezego, M. Bowen, A. Buige, D. Esposito, M. Lila, S. Komarnytsky

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Metabolic Effects of Berries with Structurally Diverse Anthocyanins

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18(2).

By: J. Overall n, S. Bonney n, M. Wilson n, A. Beermann n, M. Grace n, D. Esposito n, M. Lila n, S. Komarnytsky n

co-author countries: United States of America 🇺🇸

Contributors: J. Overall n, S. Bonney n, M. Wilson n, A. Beermann n, M. Grace n, D. Esposito n, M. Lila n, S. Komarnytsky n

author keywords: berry; gut microbiome; obesity; inflammation; functional food
MeSH headings : Animal Feed; Animals; Anthocyanins / chemistry; Anthocyanins / metabolism; Body Composition; Body Weight; Chromatography, High Pressure Liquid; Dietary Supplements; Feces / chemistry; Fruit / metabolism; Gastrointestinal Microbiome; Glucose / metabolism; Humans; Insulin Resistance; Mice; Molecular Structure; Oxygen Consumption
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Phytoecdysteroid-enriched quinoa seed leachate enhances healthspan and mitochondrial metabolism in Caenorhabditis elegans

JOURNAL OF FUNCTIONAL FOODS, 37, 1–7.

By: B. Graf*, S. Kamat*, K. Cheong*, S. Komarnytsky n, M. Driscoll* & R. Di*

co-author countries: United States of America 🇺🇸
author keywords: Aging; C elegans; Physical performance; Phytoecdysteroid; Respiration; Quinoa
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Polyphenols isolated from Acacia mearnsii bark with anti-inflammatory and carbolytic enzyme inhibitory activities

Chinese Journal of Natural Medicines, 15(11), 816–824.

By: J. Xiong n, M. Grace n, D. Esposito n, S. Komarnytsky n, F. Wang* & M. Lila n

co-author countries: China 🇨🇳 United States of America 🇺🇸

Contributors: J. Xiong n, M. Grace n, D. Esposito n, S. Komarnytsky n, F. Wang* & M. Lila n

author keywords: Acacia mearnsii; Proanthocyanidins; Anti-inflammatory; alpha-Amylase; alpha-Glucosidase
MeSH headings : Acacia / chemistry; Animals; Anti-Inflammatory Agents / isolation & purification; Anti-Inflammatory Agents / pharmacology; Carbohydrate Metabolism / drug effects; Glycoside Hydrolase Inhibitors / pharmacology; Inflammation / metabolism; Interleukin-1beta / metabolism; Lipopolysaccharides; Macrophages / drug effects; Mice; Nitric Oxide / metabolism; Nitric Oxide Synthase Type II / metabolism; Plant Bark / chemistry; Plant Extracts / chemistry; Plant Extracts / pharmacology; Polyphenols / isolation & purification; Polyphenols / pharmacology; Proanthocyanidins / pharmacology; RAW 264.7 Cells; alpha-Amylases / antagonists & inhibitors; alpha-Glucosidases / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Structural constraints and importance of caffeic acid moiety for anti-hyperglycemic effects of caffeoylquinic acids from chicory

MOLECULAR NUTRITION & FOOD RESEARCH, 61(9).

By: K. Jackson n, T. Rathinasabapathy n, D. Esposito n & S. Komarnytsky n

co-author countries: Malaysia 🇲🇾 United States of America 🇺🇸

Contributors: K. Jackson n, T. Rathinasabapathy n, D. Esposito n & S. Komarnytsky n

author keywords: Blood glucose; Cell bioenergetics; Diabetes; Dietary supplementation; Metabolic syndrome
MeSH headings : Animals; Cell Line, Tumor; Chicory / chemistry; Gluconeogenesis / drug effects; Hypoglycemic Agents / pharmacology; MAP Kinase Signaling System; Pharmacogenetics; Phosphatidylinositol 3-Kinases / physiology; Plant Roots / chemistry; Quinic Acid / analogs & derivatives; Quinic Acid / pharmacology; Rats; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Thiazolopyridines Improve Adipocyte Function by Inhibiting 11 Beta-HSD1 Oxoreductase Activity

Journal of Chemistry, 2017, 1–10.

By: T. Rathinasabapathy*, K. Palatini Jackson, Y. Thor n, A. Buru*, D. Esposito n, X. Li n, M. Pichika*, A. Hamzah*, S. Komarnytsky n

co-author countries: Malaysia 🇲🇾 United States of America 🇺🇸

Contributors: T. Rathinasabapathy*, K. Palatini Jackson, Y. Thor n, A. Buru*, D. Esposito n, X. Li n, M. Pichika*, A. Hamzah*, S. Komarnytsky n

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Chemical composition, antioxidant and anti-inflammatory properties of pistachio hull extracts

Food Chemistry, 210, 85–95.

By: M. Grace n, D. Esposito n, M. Timmers n, J. Xiong n, G. Yousef n, S. Komarnytsky n, M. Lila n

co-author countries: United States of America 🇺🇸

Contributors: M. Grace n, D. Esposito n, M. Timmers n, J. Xiong n, G. Yousef n, S. Komarnytsky n, M. Lila n

author keywords: Anacardic acids; Triterpene acids; Carotenoids; Tocopherols; Polyphenols; Anti-inflammatory
MeSH headings : Animals; Anti-Inflammatory Agents / chemistry; Anti-Inflammatory Agents / isolation & purification; Anti-Inflammatory Agents / pharmacology; Antioxidants / chemistry; Antioxidants / isolation & purification; Antioxidants / pharmacology; Cell Line; Dose-Response Relationship, Drug; Macrophages / drug effects; Macrophages / metabolism; Mice; Pistacia; Plant Extracts / chemistry; Plant Extracts / isolation & purification; Plant Extracts / pharmacology; Reactive Oxygen Species / antagonists & inhibitors; Reactive Oxygen Species / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 journal article

In vitro lipolytic, antioxidant and anti-inflammatory activities of roasted pistachio kernel and skin constituents

Food & Function, 7(10), 4285–4298.

By: M. Grace n, D. Esposito n, M. Timmers n, J. Xiong n, G. Yousef n, S. Komarnytsky n, M. Lila n

co-author countries: Belgium 🇧🇪 United States of America 🇺🇸

Contributors: M. Grace n, D. Esposito n, M. Timmers n, J. Xiong n, G. Yousef n, S. Komarnytsky n, M. Lila n

MeSH headings : Animals; Antioxidants; Cell Survival / drug effects; Cooking; Macrophages / drug effects; Macrophages / metabolism; Mice; Phytochemicals; Pistacia / chemistry; RAW 264.7 Cells; Reactive Oxygen Species; Respiratory Burst; Seeds / chemistry
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2015 journal article

1,25-Dihydroxyvitamin D-3/vitamin D receptor suppresses brown adipocyte differentiation and mitochondrial respiration

EUROPEAN JOURNAL OF NUTRITION, 54(6), 1001–1012.

By: C. Ricciardi*, J. Bae*, D. Esposito n, S. Komarnytsky n, P. Hu*, J. Chen*, L. Zhao*

co-author countries: United States of America 🇺🇸
author keywords: Vitamin D receptor; Brown adipocyte; UCP1; Mitochondrial respiration
MeSH headings : 25-Hydroxyvitamin D3 1-alpha-Hydroxylase / genetics; Adipocytes, Brown / physiology; Adipocytes, Brown / ultrastructure; Animals; Calcitriol / pharmacology; Calcitriol / physiology; Cell Differentiation / physiology; Energy Metabolism; Gene Expression; Ion Channels / genetics; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Mitochondria / metabolism; Mitochondrial Proteins / genetics; Obesity / metabolism; Oxygen Consumption / physiology; PPAR gamma / metabolism; RNA, Messenger / analysis; Receptors, Calcitriol / deficiency; Receptors, Calcitriol / genetics; Receptors, Calcitriol / physiology; Signal Transduction; Uncoupling Protein 1; Vitamin D3 24-Hydroxylase / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Alaskan seaweeds lower inflammation in RAW 264.7 macrophages and decrease lipid accumulation in 3T3-L1 adipocytes

JOURNAL OF FUNCTIONAL FOODS, 15, 396–407.

By: J. Kellogg n, D. Esposito n, M. Grace n, S. Komarnytsky n & M. Lila n

co-author countries: United States of America 🇺🇸

Contributors: J. Kellogg n, D. Esposito n, M. Grace n, S. Komarnytsky n & M. Lila n

author keywords: Seaweed; Phlorotannin; Monoglycosyldiacylglycerol; Inflammation; Insulin resistance; Fucus distichus
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Black Currant Anthocyanins Attenuate Weight Gain and Improve Glucose Metabolism in Diet-Induced Obese Mice with Intact, but Not Disrupted, Gut Microbiome

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 63(27), 6172–6180.

By: D. Esposito n, T. Damsud n, M. Wilson n, M. Grace n, R. Strauch n, X. Li n, M. Lila n, S. Komarnytsky n

co-author countries: United States of America 🇺🇸

Contributors: D. Esposito n, T. Damsud n, M. Wilson n, M. Grace n, R. Strauch n, X. Li n, M. Lila n, S. Komarnytsky n

author keywords: gastrointestinal tract; gut microbiome; obesity; inflammation; functional food
MeSH headings : Animals; Anthocyanins / administration & dosage; Anthocyanins / chemistry; Fruit / chemistry; Gastrointestinal Microbiome / drug effects; Glucose / metabolism; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity / drug therapy; Obesity / metabolism; Obesity / microbiology; Obesity / physiopathology; Plant Extracts / administration & dosage; Plant Extracts / chemistry; Ribes / chemistry; Weight Gain / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 article

Flavonoid Supplementation and Cardiovascular Disease

Bussler, W., Hildebrand, J., Mixon, C., Wagoner, T., Komarnytsky, S., & Harris, G. (2015, May). Dietary Supplements in Health Promotion, pp. 281–318.

By: W. Bussler, J. Hildebrand, C. Mixon, T. Wagoner, S. Komarnytsky & G. Harris

Source: ORCID
Added: November 11, 2019

2015 journal article

Hepatoprotective Activity of Easter Lily (Lilium longiflorum Thunb.) Bulb Extracts

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 63(44), 9722–9728.

By: W. Tang*, J. Munafo*, K. Palatini n, D. Esposito n, M. Huang*, S. Komarnytsky n, C. Ho*, T. Gianfagna*

co-author countries: United States of America 🇺🇸
author keywords: Lilium longiflorum Thunb; Easter lily; steroidal glycoside; hepatoprotective activity; hypoglycemic activity
MeSH headings : Animals; Cholesterol; Diabetes Mellitus, Type 2 / drug therapy; Diabetes Mellitus, Type 2 / metabolism; Female; Flowers / chemistry; Humans; Lilium / chemistry; Liver / drug effects; Liver / metabolism; Mice; Mice, Inbred C57BL; Molecular Structure; Plant Extracts / administration & dosage; Plant Extracts / chemistry; Protective Agents / administration & dosage; Protective Agents / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 306(10), C918–C930.

By: J. Bae*, C. Ricciardi*, D. Esposito n, S. Komarnytsky n, P. Hu*, B. Curry*, P. Brown*, Z. Gao* ...

co-author countries: United States of America 🇺🇸
author keywords: brown adipose tissue; brown adipocytes; UCP-1; pattern recognition receptor; inflammation
MeSH headings : Adipocytes / drug effects; Adipocytes / metabolism; Adipocytes / pathology; Adipose Tissue, Brown / drug effects; Adipose Tissue, Brown / metabolism; Adipose Tissue, Brown / pathology; Animals; Cell Line; Cytokines / genetics; Cytokines / metabolism; Diet, High-Fat; Electron Transport / drug effects; Gene Expression Regulation; Inflammation / genetics; Inflammation / metabolism; Inflammation / pathology; Ion Channels / genetics; Ion Channels / metabolism; Isoproterenol / pharmacology; Male; Mice; Mitochondria / drug effects; Mitochondria / metabolism; Mitochondrial Proteins / genetics; Mitochondrial Proteins / metabolism; Mitogen-Activated Protein Kinases / genetics; Mitogen-Activated Protein Kinases / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; Nod1 Signaling Adaptor Protein / genetics; Nod1 Signaling Adaptor Protein / metabolism; Nod2 Signaling Adaptor Protein / genetics; Nod2 Signaling Adaptor Protein / metabolism; Obesity / genetics; Obesity / metabolism; Obesity / pathology; Promoter Regions, Genetic; RNA, Messenger / genetics; RNA, Messenger / metabolism; Signal Transduction; Toll-Like Receptor 2 / genetics; Toll-Like Receptor 2 / metabolism; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Uncoupling Protein 1
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Cytotoxic Effects of Ellagitannins Isolated from Walnuts in Human Cancer Cells

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 66(8), 1304–1314.

By: V. Le*, D. Esposito n, M. Grace n, D. Ha*, A. Pham*, A. Bortolazzo*, Z. Bevens*, J. Kim* ...

co-author countries: United States of America 🇺🇸

Contributors: V. Le*, D. Esposito n, M. Grace n, D. Ha*, A. Pham*, A. Bortolazzo*, Z. Bevens*, J. Kim* ...

MeSH headings : 3T3 Cells; Animals; Apoptosis / drug effects; Cell Line, Tumor; Cyclin B1 / metabolism; Cytochromes c / metabolism; Diet; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hydrolyzable Tannins / pharmacology; Juglans / chemistry; MCF-7 Cells; Mice; Mice, Nude; Mitochondria / drug effects; Nuts / chemistry; Plant Extracts / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Inhibitory Effects of Wild Blueberry Anthocyanins and Other Flavonoids on Biomarkers of Acute and Chronic Inflammation in Vitro

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 62(29), 7022–7028.

By: D. Esposito n, A. Chen n, M. Grace n, S. Komarnytsky n & M. Lila n

co-author countries: United States of America 🇺🇸

Contributors: D. Esposito n, A. Chen n, M. Grace n, S. Komarnytsky n & M. Lila n

author keywords: Vaccinium angustifolium; lowbush blueberry; polyphenols; proanthocyanidins; chlorogenic acid
MeSH headings : Acute Disease; Animals; Anthocyanins / pharmacology; Base Sequence; Biomarkers / metabolism; Blueberry Plants / chemistry; Cell Line; Chromatography, High Pressure Liquid; Chronic Disease; DNA Primers; In Vitro Techniques; Inflammation / metabolism; Macrophages / drug effects; Macrophages / metabolism; Mice; Polymerase Chain Reaction
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Acceleration of cutaneous wound healing by brassinosteroids

WOUND REPAIR AND REGENERATION, 21(5), 688–696.

By: D. Esposito*, T. Rathinasabapathy*, B. Schmidt*, M. Shakarjian*, S. Komarnytsky n & I. Raskin*

co-author countries: Malaysia 🇲🇾 United States of America 🇺🇸

Contributors: D. Esposito*, T. Rathinasabapathy*, B. Schmidt*, M. Shakarjian*, S. Komarnytsky n & I. Raskin*

MeSH headings : Administration, Topical; Animals; Blotting, Western; Brassinosteroids / pharmacology; Cell Proliferation; Cells, Cultured; Intercellular Adhesion Molecule-1 / drug effects; Intercellular Adhesion Molecule-1 / metabolism; Male; Mice; Mice, Inbred C57BL; Signal Transduction / drug effects; Skin / injuries; Skin / pathology; Transforming Growth Factor beta / drug effects; Transforming Growth Factor beta / metabolism; Tumor Necrosis Factor-alpha / drug effects; Tumor Necrosis Factor-alpha / metabolism; Wound Healing / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Effects of Pregnane Glycosides on Food Intake Depend on Stimulation of the Melanocortin Pathway and BDNF in an Animal Model

Journal of Agricultural and Food Chemistry, 61(8), 1841–1849.

By: S. Komarnytsky n, D. Esposito n, T. Rathinasabapathy*, A. Poulev* & I. Raskin*

co-author countries: Ukraine 🇺🇦 United States of America 🇺🇸

Contributors: S. Komarnytsky n, D. Esposito n, T. Rathinasabapathy*, A. Poulev* & I. Raskin*

author keywords: appetite; satiety; body weight; milkweed; Asclepias
MeSH headings : Animals; Appetite / drug effects; Asclepias / chemistry; Brain-Derived Neurotrophic Factor / genetics; Brain-Derived Neurotrophic Factor / metabolism; Cell Line, Tumor; Eating / drug effects; Female; Glycosides / administration & dosage; Humans; Male; Melanocortins / metabolism; Models, Animal; Plant Extracts / administration & dosage; Pregnanes / administration & dosage; Rats; Rats, Wistar
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2013 journal article

Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cells

JOURNAL OF CELLULAR PHYSIOLOGY, 228(5), 1120–1126.

By: S. Komarnytsky n, D. Esposito n, A. Poulev* & I. Raskin*

co-author countries: United States of America 🇺🇸
MeSH headings : 3-Hydroxysteroid Dehydrogenases / antagonists & inhibitors; 3-Hydroxysteroid Dehydrogenases / biosynthesis; Adrenal Cortex Hormones / metabolism; Androstenedione / analogs & derivatives; Animals; Cell Line, Tumor; Cholesterol Side-Chain Cleavage Enzyme / antagonists & inhibitors; Cholesterol Side-Chain Cleavage Enzyme / biosynthesis; Corticosterone / biosynthesis; Corticosterone / metabolism; Cortisone / metabolism; Glycosides / administration & dosage; Humans; Pregnanes / administration & dosage; Progesterone / analogs & derivatives; Progesterone / biosynthesis; Steroid 11-beta-Hydroxylase / antagonists & inhibitors; Steroid 11-beta-Hydroxylase / biosynthesis; Steroid 17-alpha-Hydroxylase / antagonists & inhibitors; Steroid 17-alpha-Hydroxylase / biosynthesis; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Steroidal glycosides from the bulbs of Easter lily (Lilium longiflorum Thunb.) promote dermal fibroblast migration in vitro

JOURNAL OF ETHNOPHARMACOLOGY, 148(2), 433–440.

By: D. Esposito n, J. Munafo*, T. Lucibello*, M. Baldeon*, S. Komarnytsky n & T. Gianfagna*

co-author countries: Ecuador 🇪🇨 United States of America 🇺🇸
author keywords: Lilium longiflorum Thunb.; Steroidal glycoside; Furostanol saponin; Transforming growth factor beta; Nitric oxide; Wound healing
MeSH headings : 3T3 Cells; Animals; Carbohydrate Sequence; Cell Movement / drug effects; Cell Proliferation / drug effects; Cells, Cultured; Dermis / cytology; Dermis / drug effects; Dermis / metabolism; Ethnopharmacology / methods; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Glycosides / chemistry; Glycosides / pharmacology; Human Umbilical Vein Endothelial Cells; Humans; Lilium / chemistry; Mice; Molecular Sequence Data; Nitric Oxide / metabolism; Plant Extracts / chemistry; Plant Extracts / pharmacology; Plant Roots / chemistry; Skin / cytology; Skin / drug effects; Skin / metabolism; Steroids / chemistry; Steroids / pharmacology; Transforming Growth Factor beta / metabolism; Wound Healing / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Hypoglycemic effects of brassinosteroid in diet-induced obese mice

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 303(5), E652–E658.

By: D. Esposito*, P. Kizelsztein*, S. Komarnytsky n & I. Raskin*

co-author countries: United States of America 🇺🇸
author keywords: homobrassinolide; glucose; insulin resistance; diabetes; phosphoenolpyruvate carboxykinase
MeSH headings : AMP-Activated Protein Kinases / metabolism; Animals; Brassinosteroids / administration & dosage; Brassinosteroids / therapeutic use; Cell Line; Cyclic AMP / antagonists & inhibitors; Cyclic AMP / metabolism; Diet, High-Fat / adverse effects; Dietary Supplements; Gene Expression Regulation; Glucose-6-Phosphatase / genetics; Glucose-6-Phosphatase / metabolism; Hyperglycemia / prevention & control; Hypoglycemic Agents / therapeutic use; Insulin Resistance; Liver / enzymology; Liver / metabolism; Male; Mice; Mice, Inbred C57BL; Obesity / blood; Obesity / diet therapy; Obesity / etiology; Phosphoenolpyruvate Carboxykinase (ATP) / genetics; Phosphoenolpyruvate Carboxykinase (ATP) / metabolism; Phosphorylation; Protein Processing, Post-Translational; RNA, Messenger / metabolism; Random Allocation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Modulation of muscle mass and myogenic stem cells with natural products

Planta Medica, 78(11).

By: D. Esposito n, I. Raskin* & S. Komarnytsky n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: February 5, 2020

2012 conference paper

Modulation of muscle mass and myogenic stem cells with natural products

Planta Medica, 78(11), 1096–1096.

By: D. Esposito, I. Raskin & S. Komarnytsky

Source: NC State University Libraries
Added: August 6, 2018

2012 article

Plant-Derived Antibodies for Academic, Industrial, and Therapeutic Applications

Komarnytsky, S., & Borisjuk, N. (2012, April). Antibody-Mediated Drug Delivery Systems, pp. 365–381.

By: S. Komarnytsky n & N. Borisjuk*

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: November 11, 2019

2011 journal article

Akt-Dependent Anabolic Activity of Natural and Synthetic Brassinosteroids in Rat Skeletal Muscle Cells

Journal of Medicinal Chemistry, 54(12), 4057–4066.

By: D. Esposito*, T. Rathinasabapathy*, A. Poulev*, S. Komarnytsky* & I. Raskin*

co-author countries: United States of America 🇺🇸

Contributors: D. Esposito*, T. Rathinasabapathy*, A. Poulev*, S. Komarnytsky* & I. Raskin*

MeSH headings : Anabolic Agents / chemical synthesis; Anabolic Agents / chemistry; Anabolic Agents / pharmacology; Animals; Cell Line; Cell Survival / drug effects; Cholestanones / chemical synthesis; Cholestanones / chemistry; Cholestanones / pharmacology; Mice; Muscle, Skeletal / cytology; Muscle, Skeletal / drug effects; Phosphorylation; Proto-Oncogene Proteins c-akt / metabolism; Rats; Stereoisomerism; Structure-Activity Relationship
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

Anabolic effect of plant brassinosteroid

FASEB JOURNAL, 25(10), 3708–3719.

By: D. Esposito*, S. Komarnytsky*, S. Shapses* & I. Raskin*

co-author countries: United States of America 🇺🇸
author keywords: homobrassinolide; protein synthesis; muscle mass
MeSH headings : Anabolic Agents / administration & dosage; Anabolic Agents / pharmacology; Animals; Body Composition / drug effects; Cells; Cholestanones / administration & dosage; Cholestanones / pharmacology; Dietary Proteins; Lethal Dose 50; Male; Molecular Structure; Muscle Fibers, Skeletal / drug effects; Muscle, Skeletal / cytology; Muscle, Skeletal / drug effects; Orchiectomy; Rats; Rats, Wistar
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Potato protease inhibitors inhibit food intake and increase circulating cholecystokinin levels by a trypsin-dependent mechanism

International Journal of Obesity, 35(2), 236–243.

By: S. Komarnytsky*, A. Cook* & I. Raskin*

co-author countries: United States of America 🇺🇸
author keywords: satiety; body weight; cholecystokinin; protease inhibitors; potato
MeSH headings : Animals; Cells, Cultured; Cholecystokinin / metabolism; Duodenum / metabolism; Energy Intake / drug effects; Energy Intake / physiology; Gastric Emptying / drug effects; Male; Phytotherapy; Plant Preparations / administration & dosage; Plant Preparations / pharmacology; Protease Inhibitors / administration & dosage; Protease Inhibitors / pharmacology; Proteins / metabolism; Rats; Rats, Wistar; Satiation / drug effects; Satiation / physiology; Solanum tuberosum / enzymology; Trypsin Inhibitors / administration & dosage; Trypsin Inhibitors / pharmacology
Source: ORCID
Added: November 11, 2019

2009 journal article

20-Hydroxyecdysone decreases weight and hyperglycemia in a diet-induced obesity mice model

American Journal of Physiology - Endocrinology and Metabolism, 296(3).

By: P. Kizelsztein, D. Govorko, S. Komarnytsky*, A. Evans, Z. Wang, W. Cefalu, I. Raskin

author keywords: gluconeogenic enzymes; adiponectin; obesity and diabetes
MeSH headings : AMP-Activated Protein Kinases / metabolism; Adiponectin / blood; Animals; Blood Glucose / drug effects; Blood Glucose / metabolism; Body Weight / drug effects; Carcinoma, Hepatocellular; Cells, Cultured; Dietary Fats / pharmacology; Ecdysterone / chemistry; Ecdysterone / metabolism; Ecdysterone / pharmacology; Glucose Intolerance / drug therapy; Glucose Intolerance / metabolism; Hyperglycemia / drug therapy; Hyperglycemia / metabolism; Insulin / blood; Insulin Resistance; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Obesity / drug therapy; Obesity / metabolism; Phosphatidylinositol 3-Kinases / metabolism; Rats; STAT1 Transcription Factor / drug effects
Source: ORCID
Added: November 11, 2019

2009 journal article

Oral administration of triptolide ameliorates the clinical signs of experimental autoimmune encephalomyelitis (EAE) by induction of HSP70 and stabilization of NF-κB/IκBα transcriptional complex

Journal of Neuroimmunology, 217(1-2), 28–37.

By: P. Kizelsztein*, S. Komarnytsky* & I. Raskin*

co-author countries: United States of America 🇺🇸
author keywords: EAE; Hsp70; Inflammation; NF-kappa B; Oral; Triptolide
MeSH headings : Administration, Oral; Analysis of Variance; Animals; Cell Line, Transformed; Cytokines / metabolism; Cytoplasm / drug effects; Cytoplasm / metabolism; Disease Models, Animal; Diterpenes / administration & dosage; Diterpenes / pharmacology; Encephalomyelitis, Autoimmune, Experimental / chemically induced; Encephalomyelitis, Autoimmune, Experimental / metabolism; Encephalomyelitis, Autoimmune, Experimental / pathology; Encephalomyelitis, Autoimmune, Experimental / prevention & control; Epoxy Compounds / administration & dosage; Epoxy Compounds / pharmacology; HSP70 Heat-Shock Proteins / genetics; HSP70 Heat-Shock Proteins / metabolism; I-kappa B Proteins / metabolism; Immunoprecipitation; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / pharmacology; Lymph Nodes / cytology; Macrophages / drug effects; Macrophages / metabolism; Mice; Myelin Proteolipid Protein; NF-KappaB Inhibitor alpha; NF-kappa B / metabolism; Peptide Fragments; Phenanthrenes / administration & dosage; Phenanthrenes / pharmacology; Phosphorylation / drug effects; Phytotherapy / methods; RNA, Messenger / metabolism; Signal Transduction / drug effects; Time Factors; Tripterygium / chemistry; Up-Regulation / drug effects
Source: ORCID
Added: November 11, 2019

2007 journal article

Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line

American Journal of Physiology - Endocrinology and Metabolism, 293(6).

By: D. Govorko, S. Logendra, Y. Wang, D. Esposito, S. Komarnytsky*, D. Ribnicky, A. Poulev, Z. Wang, W. Cefalu, I. Raskin

author keywords: phosphoenolpyruvate carboxykinase; polyphenols; diabetes
MeSH headings : Animals; Artemisia / chemistry; Cell Line, Tumor; Chalcones / analysis; Chalcones / isolation & purification; Chalcones / pharmacology; Chromones / analysis; Chromones / isolation & purification; Chromones / pharmacology; Cyclic AMP / analogs & derivatives; Cyclic AMP / pharmacology; Dexamethasone / pharmacology; Enzyme Inhibitors / pharmacology; Flavonoids / analysis; Flavonoids / isolation & purification; Flavonoids / pharmacology; Gene Expression / drug effects; Gluconeogenesis / drug effects; Glucose / metabolism; Hypoglycemic Agents / analysis; Hypoglycemic Agents / isolation & purification; Hypoglycemic Agents / pharmacology; Insulin / pharmacology; Morpholines / pharmacology; Phenols / analysis; Phenols / isolation & purification; Phenols / pharmacology; Phosphoenolpyruvate Carboxykinase (GTP) / genetics; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation / drug effects; Plant Extracts / pharmacology; Plant Shoots / chemistry; Polyphenols; Proto-Oncogene Proteins c-akt / metabolism; Pyrazoles / pharmacology; Pyrimidines / pharmacology; RNA, Messenger / genetics; RNA, Messenger / metabolism; Rats; Thionucleotides / pharmacology
Source: ORCID
Added: November 11, 2019

2007 journal article

Preparative isolation and identification of tyrosinase inhibitors from the seeds of Garcinia kola by high-speed counter-current chromatography

Journal of Chromatography A, 1151(1-2), 45–50.

By: C. Okunji*, S. Komarnytsky*, G. Fear*, A. Poulev*, D. Ribnicky*, P. Awachie, Y. Ito*, I. Raskin*

co-author countries: United States of America 🇺🇸
author keywords: Garcinia kola; tyrosinase; biflavanones; high-speed counter-current chromatography (HSCCC)
MeSH headings : Countercurrent Distribution / methods; Flavonoids / chemistry; Flavonoids / isolation & purification; Garcinia kola / chemistry; Molecular Structure; Peptides / chemistry; Peptides / isolation & purification; Reproducibility of Results; Seeds / chemistry
Source: ORCID
Added: November 11, 2019

2007 journal article

Protease inhibitors and their peptidomimetic derivatives as potential drugs

Pharmacology and Therapeutics, 113(2), 354–368.

By: G. Fear*, S. Komarnytsky* & I. Raskin*

co-author countries: United States of America 🇺🇸
author keywords: protease; protease inhibitors; therapeutic application; clinical trials; approved drugs
MeSH headings : Animals; Communicable Diseases / enzymology; Diabetes Mellitus / enzymology; Fungi / enzymology; Humans; Inflammation / enzymology; Neoplasms / enzymology; Peptides / pharmacology; Plant Extracts / pharmacology; Protease Inhibitors / pharmacology; Viruses / enzymology
Source: ORCID
Added: November 11, 2019

2006 journal article

Cosecretion of protease inhibitor stabilizes antibodies produced by plant roots

Plant Physiology, 141(4), 1185–1193.

By: S. Komarnytsky*, N. Borisjuk*, N. Yakoby*, A. Garvey* & I. Raskin*

co-author countries: United States of America 🇺🇸
MeSH headings : Antibodies, Monoclonal / biosynthesis; Antibodies, Monoclonal / genetics; Antibodies, Monoclonal / metabolism; Calreticulin / metabolism; Culture Media; Humans; Hydroponics; Immunoglobulin G / biosynthesis; Plant Roots / metabolism; Plants, Genetically Modified / metabolism; Protein Engineering / methods; Recombinant Proteins / biosynthesis; Serine Proteinase Inhibitors / genetics; Serine Proteinase Inhibitors / metabolism; Tobacco / genetics; Trypsin Inhibitor, Bowman-Birk Soybean / genetics
Source: ORCID
Added: November 11, 2019

2004 journal article

A quick and efficient system for antibiotic-free expression of heterologous genes in tobacco roots

Plant Cell Reports, 22(10), 765–773.

By: S. Komarnytsky*, A. Gaume*, A. Garvey*, N. Borisjuk* & I. Raskin*

co-author countries: United States of America 🇺🇸
author keywords: plant genetic engineering; selectable marker; rol genes; hairy roots; recombinant protein production
MeSH headings : Agrobacterium tumefaciens / genetics; Culture Media; Gene Expression; Genetic Markers; Genetic Vectors; Glucuronidase / metabolism; Plant Roots / genetics; Plant Roots / metabolism; Plants, Genetically Modified; Recombinant Proteins / isolation & purification; Recombinant Proteins / metabolism; Tobacco / genetics; Transformation, Genetic
Source: ORCID
Added: November 11, 2019

2003 article

Functional Analysis of Promoter Elements in Plants

Genetic Engineering, pp. 113–141.

By: S. Komarnytsky* & N. Borisjuk*

co-author countries: United States of America 🇺🇸
MeSH headings : Cell Nucleus / metabolism; Plants / genetics; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Transcription Factors / metabolism; Transcription, Genetic
Source: ORCID
Added: November 11, 2019

2003 journal article

Functional analysis of promoter elements in plants.

Genetic Engineering, 25, 113–141. http://www.scopus.com/inward/record.url?eid=2-s2.0-3543141756&partnerID=MN8TOARS

By: S. Komarnytsky & N. Borisjuk

Source: ORCID
Added: November 11, 2019

2003 journal article

Rhizosecretion of recombinant proteins from plant hairy roots

Plant Cell Reports, 21(12), 1188–1193.

By: A. Gaume*, S. Komarnytsky*, N. Borisjuk* & I. Raskin*

co-author countries: United States of America 🇺🇸
author keywords: hairy roots; recombinant proteins; rhizosecretion; transgenic plants
MeSH headings : Alkaline Phosphatase / genetics; Cloning, Molecular / methods; Gene Expression Regulation; Humans; Plant Roots / metabolism; Plants, Genetically Modified; Recombinant Proteins / metabolism; Rhizobium / genetics; Seeds; Tobacco / genetics
Source: ORCID
Added: November 11, 2019

2002 journal article

Plants and human health in the twenty-first century

Trends in Biotechnology, 20(12), 522–531.

By: I. Raskin*, D. Ribnicky*, S. Komarnytsky*, N. Ilic, A. Poulev, N. Borisjuk*, A. Brinker*, D. Moreno* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Dietary Supplements / classification; Drugs, Chinese Herbal / therapeutic use; Food, Fortified / classification; Food, Genetically Modified; Forecasting; Humans; Phytotherapy / methods; Phytotherapy / trends; Plant Extracts / classification; Plant Extracts / therapeutic use; Plants, Genetically Modified / metabolism; Plants, Medicinal; Recombinant Proteins / biosynthesis; Recombinant Proteins / therapeutic use; Technology, Pharmaceutical / methods; Technology, Pharmaceutical / trends
Source: ORCID
Added: November 11, 2019

2001 journal article

Phylogenetic tree of the australian species of Nicotiana based on the random amplified polymorphic DNA

Biopolymers and Cell, 17(4), 278–282.

By: S. Komarnytsky* & I. Komarnytsky*

co-author countries: Ukraine 🇺🇦
Source: ORCID
Added: November 11, 2019

2000 journal article

Production of recombinant proteins in tobacco guttation fluid

Plant Physiology, 124(3), 927–933. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033729827&partnerID=MN8TOARS

By: S. Komarnytsky, N. Borisjuk, L. Borisjuk, M. Alam & I. Raskin

Source: ORCID
Added: November 11, 2019

2000 journal article

Tobacco ribosomal DNA spacer element stimulates amplification and expression of heterologous genes

Nature Biotechnology, 18(12), 1303–1306.

By: N. Borisjuk*, L. Borisjuk, S. Komarnytsky*, S. Timeva*, V. Hemleben*, Y. Gleba*, I. Raskin*

co-author countries: Germany 🇩🇪 Ukraine 🇺🇦 United States of America 🇺🇸
author keywords: gene amplification; enhanced transcription; protein expression; transgenic plants; recombinant proteins
MeSH headings : Acetolactate Synthase / genetics; Acetolactate Synthase / metabolism; Base Sequence; DNA, Ribosomal Spacer / genetics; Drug Resistance; Gene Amplification; Gene Expression; Herbicides / pharmacology; Molecular Sequence Data; Plants, Genetically Modified; Plants, Toxic; Recombinant Proteins / biosynthesis; Recombinant Proteins / genetics; Tobacco / genetics; Transcription, Genetic; Transgenes
Source: ORCID
Added: November 11, 2019

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