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NCSU Libraries Focus Online

Volume 27 number 2 - Winter 2007

Genetics and Plant Genomics: Building Unique Collections for the Twenty-first Century

By Bob Sotak, Collection Management, and Greg Raschke, Collections and Scholarly Communication

Genetics, the study of heredity, is considered to have begun with the plant hybridization experiments of Gregor Mendel in the middle of the nineteenth century. In the twentieth century, North Carolina State University established an excellent reputation for its own research in plant and forest genetics. The range of this research illustrates why the Libraries’ collections must constantly evolve to meet the needs of faculty.

S. G. Stephens, the first chair of the genetics faculty, was an international authority on the genetics of cotton. Geneticist John Scandalios is well known for his work in developmental and biochemical genetics. Charles S. Levings III of the Department of Genetics became a member of the National Academy of Sciences and made significant advances in the understanding of plant mitochondrial genetics, especially traits such as cytoplasmic male sterility in maize. Charles Stuber, also with the genetics department, studied quantitative inheritance in plants and pioneered the use of molecular markers to improve traits such as grain yield.

Plant genetics research at NCSU is not limited to the genetics department, but is also an area of research in the departments of forestry, crop science, horticulture, botany, and plant pathology. Bruce Zobel of forestry specialized in forest genetics and tree improvement and started the Industrial Forest Tree Improvement Cooperative. Major Goodman of crop science, a member of the National Academy of Sciences, achieved recognition for his work in using maize germplasm resources in breeding. Professor of Crop Science Dan Gerstel specialized in the cytogenetics of tobacco and cotton.

As a land-grant institution, genetics research at NC State has a strong applied aspect. Many of the findings made in plant and forest genetics and genomics research are ultimately used in plant and agricultural biotechnology and other areas.

Genomics is different from genetics in that it studies the entire genome or genetic complement of an organism. It has a more recent origin than genetics and came to the public’s attention with the sequencing of the human genome, which was completed in 2003. North Carolina State University researchers have already made significant contributions in plant genomics. Ron Sederoff, a member of the Department of Forestry and of the National Academy of Sciences, is well known for the application of genomics to forest-tree species such as loblolly pine. Ralph Dean of plant pathology collaborated on sequencing the rice genome and is the leader of the Rice Blast Genome Initiative, which is mapping and sequencing the rice blast pathogen Magnaporthe grisea. Steven Lommel and Charles Opperman, both with the plant pathology department, received a $17.6 million grant from Philip Morris USA to map and determine the nucleotide sequence of the tobacco genome. Their Tobacco Genome Initiative should provide valuable data that can be applied to other plant species.

The importance of genomics at NCSU is reflected in the graduate programs in functional genomics and bioinformatics that have more than 100 professors listed as genomic sciences faculty. In addition to the College of Agriculture and Life Sciences and the College of Natural Resources, genomic sciences have representatives from the colleges of Engineering, Veterinary Medicine, and Physical and Mathematical Sciences. The establishment of the Genome Research Laboratory on Centennial Campus has further enhanced researchers’ abilities to do high-throughput genomics research.

With such breadth and quality of research at NC State in the areas of genetics and plant and forestry genomics, the Special Collections Research Center has initiated efforts to build its genetics and genomics holdings to enhance the already excellent body of materials in the general collection. Prominent NC State faculty such as Zobel, Sederoff, Goodman, Gerstel, and Stuber have either donated or promised to donate their papers and research documentation to the center.

In 2005 the Libraries added Mary Dell Chilton’s papers, documenting her Nobel Prize-nominated graduate and post-graduate research that led to the discovery of the technique by which all genetic manipulation of plant species is done. In a recent article appearing in the International Journal of Developmental Biology, Chilton’s research was ranked eighth in a chronological list of the most important milestones in the history of plant developmental biology. To complement the growth of papers from prominent scholars, the Libraries continually adds to its Special Collections holdings rare and seminal books documenting the establishment and growth of genetics and plant genomics as research disciplines.

The path from Mendel to sequencing genomes and creating the science of the twenty-first century has taken contributions from many scholars, including a number of prominent researchers at NC State working in a variety of disciplines. The NCSU Libraries is dedicated to documenting NC State’s contributions to plant and forestry genomics while capturing seminal contributions in the history of genetics scholarship. The Libraries welcomes support for this important collecting initiative and encourages other donors to expand the research center’s collections. Those who would like to support the processing, growth, and possible digitization of these resources should call either Jim Mulvey, director of library development, at (919) 515-3339, or Greg Raschke, associate director for collections and scholarly communication, at (919) 515-7188.

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