Mary-Dell Chilton Papers 1947-1999

Creator
Chilton, Mary-Dell, 1939-
Size
9.25 linear feet
Location

For current information on the location of these materials, please consult the Special Collections Research Center Reference Staff.

Call number
MC 00376

The Mary-Dell Chilton Papers include laboratory records, correspondence, notes, manuscripts, reprints, articles, and photographs from 1947 through 1999 documenting Chilton's career as a plant geneticist. The bulk of the records are from the late 1970s and early 1980s.

Mary-Dell Chilton has worked as a plant geneticist and genetic engineer throughout her career at the University of Washington, Washington University in St. Louis, and at Syngenta Biotechnology, Inc. in Research Triangle Park in North Carolina.

Biographical/historical note

Mary-Dell Chilton was born in Indianapolis, Indiana, on February 2, 1939. After receiving a B.S. in chemistry from the University of Illinois, Urbana, Mary-Dell Chilton continued to study at the University of Illinois, completing her Ph.D. in Chemistry in 1967 with a dissertation entitled Transforming Activity in Single Stranded DNA from Bacillus Subtilis. She then went on to complete post-doctoral fellowships at the University of Washington, Seattle, until 1971, when she received a faculty position at the same university. Chilton remained at the University of Washington until 1979 when she accepted a faculty position at Washington University in St. Louis. Chilton's research teams at the universities first demonstrated that the genes responsible for causing disease could be removed from the bacterium without adversely affecting its ability to insert its own DNA into a plant cell. Chilton and her collaborators at Washington University were also the first to produce transgenic plants.

In 1983, Mary-Dell Chilton left Washington University and accepted a position in the private sector at CIBA-Geigy Corporation, which later became Syngenta Biotechnology, Inc. (SBI) in Research Triangle Park, North Carolina. Her tenure there spanned both research and administrative roles, including vice president of agricultural biotechnology, distinguished science fellow, and principal scientist. In 2002, Chilton's contributions to the development of plant biotechnology earned her the Benjamin Franklin Medal in Life Sciences from the Franklin Institute. In 2011 she received the Presidential Award from the Crop Science Society of America.

Chilton's current research (as of September 2011) is directed at improving the technology for introducing new genes into plants. Specifically her work has involved gene stacking (keeping all genes in one place) and targeting (getting genes to insert at a particular place).

Mary-Dell Chilton was married to Dr. Scott Chilton, who was a professor of botany in the College of Agriculture and Life Sciences at North Carolina State University from 1983 to 2004. In 2004, a few weeks before Scott Chilton's untimely death, Mary-Dell Chilton and her husband completed plans to create an endowment supporting the collections of the NCSU Libraries.

Scope/content

The Mary-Dell Chilton Papers include laboratory records, correspondence, notes, manuscripts, reprints, articles, and photographs, 1947-1999, documenting Chilton's career as a plant geneticist. The bulk of the records are from the late 1970s and early 1980s.

Physical description

17 archival boxes, 1 carton

Arrangement

The Mary-Dell Chilton Papers are organized into six series:

  • Laboratory Records
  • ,
  • Research Files
  • ,
  • Publications and Manuscripts
  • ,
  • Teaching and Advising Files
  • ,
  • Correspondence
  • , and
  • Subject Files
. There is also one carton of unprocessed papers.

Use of these materials

The nature of the NCSU Libraries' Special Collections means that copyright or other information about restrictions may be difficult or even impossible to determine despite reasonable efforts. The NCSU Libraries claims only physical ownership of most Special Collections materials.

The materials from our collections are made available for use in research, teaching, and private study, pursuant to U.S. Copyright law. The user must assume full responsibility for any use of the materials, including but not limited to, infringement of copyright and publication rights of reproduced materials. Any materials used for academic research or otherwise should be fully credited with the source.

Preferred Citation

[Identification of item], Mary-Dell Chilton Papers, MC 00376, Special Collections Research Center, North Carolina State University Libraries, Raleigh, NC

Source of acquisition

Gift of Mary-Dell Chilton, 2005 June (Accession number 2005-0005)

Processing information

Processed by Nathan Crowe and Stephanie Horowitz, 2006 August; encoded by Stephanie Horowitz, 2006 August.

Laboratory Records 1962-1981
Size: 2.5 linear feet

This series contains Mary-Dell Chilton's laboratory notebooks and other records from her laboratory experiments. Many were originally contained in binders labeled by experiment or subject. The records contain a great deal of information regarding DNA experimentation and other genetics experiments.

5 archival boxes

Brute Force Experiments, Folder 1 of 2 1976 Summer
Box 1, Folder 1
Brute Force Experiments, Folder 2 of 2 1976 Summer
Box 1, Folder 2
Brute Force Experiments II 1976 Summer
Box 1, Folder 3
Clones - Plasmid/Plant 1978
Box 1, Folder 4
Corn 1968
Box 1, Folder 5
Crown Gall 1973-1975
Box 2, Folder 1
Digests - Randall Saiki 1978-1979
Box 2, Folder 2
DNA/RNA on HA. I. B. subtilis 1969
Box 2, Folder 3
DNA/RNA on HA. II. Unique Mouse, Mouse Genome Fractionation 1969
Box 2, Folder 4
DNA/RNA on HA. II. Unique Mouse, Mouse DNA/RNA on HA 1969
Box 2, Folder 5
Graduate Laboratory Work 1962-1963
Box 2, Folder 6
M-13 Cloning/DNA Sequencing 1981
Box 2, Folder 7
Methods undated
Box 3, Folder 1
Mouse 1970 March 27-1970 August
Box 3, Folder 2
Nopaline Plasmids, Cryptopine Plasmids 1978-1979
Box 3, Folder 3
Notes 1979
Box 3, Folder 4
Octopine - Nopaline, Book 2, Folder 1 of 2 1977
Box 3, Folder 5
Octopine - Nopaline, Book 2, Folder 2 of 2 1977
Box 3, Folder 6
Plasmid DNA Isolation, Restriction Endonuclear Experiments 1976
Box 3, Folder 7
Plasmid Genetics; Transformation 1975 September 17-1976 March 27
Box 3, Folder 8
Plasmids - Common Bond Experiments - Cloning 1977-1978
Box 4, Folder 1
Radioactivity Log (Archives) undated
Box 4, Folder 2
"Randy Papers" - Enzyme Preps., Plasmid Clones, Alkaline Gels, DNA Concentrations, Plasmid Mapping, Misc., Methods 1978-1979
Box 4, Folder 3
Sequencing 1978-1979
Box 4, Folder 4
Tomato Satellite 1972 October 16-1974 January 24
Box 4, Folder 5
Gel Films [oversize] undated
Legal box 17, Folder 1
DNA Digests and Eco Plants [oversize] 1978-1979
Legal box 17, Folder 2
Research Files 1947-1982
Size: 2.25 linear feet

This series includes material related to Mary-Dell Chilton's research on plants, plant genetics, genetic engineering, and other subjects in which she was professionally interested. It contains articles and reprints written by other scientists, as well as many of Chilton's own research notes. The series also includes professional activity information related to Chilton's research, such as grant applications and information on professional conferences attended by Chilton.

5 archival boxes

5B and 0B Maize 1968-1973
Box 5, Folder 1
ACS [American Cancer Society] Proposal 1974
Box 5, Folder 2
ACS [American Cancer Society] Grant Application, Molecular Basis of Crown Gall Tumor Genesis 1980 March 25
Box 5, Folder 3
Agrobacterium References 1980
Box 5, Folder 4
American Association for the Advancement of Science Annual Meeting Program 1979 January
Box 5, Folder 5
B. subtilis Transformation 1969-1970
Box 5, Folder 6
Blattner, Structure of the Constant...Heavy Chain Messenger RNA 1979 December 14
Box 5, Folder 7
Cloned Tumor DNA Binder, Notes and Articles 1969-1975
Box 5, Folder 8
Cloning Origins 1978
Box 5, Folder 9
Cloning Technology 1976, 1978
Box 5, Folder 10
Corn 1947-1973
Box 5, Folder 11
Development of a Tumor-Inducing Plasmid Vector for Plant Genetic Engineering, "Unfinished Symphony," Folder 1 of 2 1980-1982
Box 5, Folder 12
Development of a Tumor-Inducing Plasmid Vector for Plant Genetic Engineering, "Unfinished Symphony," Folder 2 of 2 1980-1982
Box 5, Folder 13
DNA Articles 1979, undated
Box 5, Folder 14
DNA-RNA Hybrid 1960-1969
Box 5, Folder 15
DNA Sequencing undated
Box 5, Folder 16
DNA Transformation Articles 1958-1964
Box 6, Folder 1
DNA Transformation Articles 1965-1966
Box 6, Folder 2
DNA Transformation Articles 1967-1968
Box 6, Folder 3
DNA Transformation Articles 1969-1971
Box 6, Folder 4
DNA Transformation Articles 1972-1975
Box 6, Folder 5
DNA Transformation Meetings 1967-1968
Box 6, Folder 6
DNA Transformation Notes 1961-1973
Box 6, Folder 7
Drug Resistance Gene Sequence 1979-1982
Box 6, Folder 8
EMBO [European Molecular Biology Organization] Meeting, Molecular Biologists Look at Green Plants 1980
Box 6, Folder 9
Farley-Chilton Enterprises, Inc. Grant and Budget Information 1980-1981
Box 6, Folder 10
Genetic Engineering 1980-1981
Box 7, Folder 1
Genetic Engineering Articles 1978 July
Box 7, Folder 2
George Jen Proposal, In Vivo Suppression of Plant Nonsense Mutants Award Application 1981 May 29
Box 7, Folder 3
Gordon Conference on Plant Molecular Biology 1980
Box 7, Folder 4
Grant Application, Molecular Basis of Crown Gall Tumorigenesis 1975 March 26
Box 7, Folder 5
Images and German Articles undated
Box 7, Folder 6
Insulin Genes - Howard Goodman 1979
Box 7, Folder 7
Ken Barton - Data undated
Box 7, Folder 8
Ken Barton - Data, Plasmids and Bugs Freezer Collection undated
Box 7, Folder 9
Ledoux 1975-1979
Box 7, Folder 10
Mapping Cuts in Clones 1980 September 1, undated
Box 7, Folder 11
Mapping Cuts in Clones undated
Box 7, Folder 12
Mapping Cuts in Clones, BAM 3A and 6, ECO 18 and 26 undated
Box 7, Folder 13
Mapping Cuts in Clones, BAM 14A and BAM 9 1982 March 3, undated
Box 7, Folder 14
Mapping Cuts in Clones, Biohazards, Draft of T37 Map Paper undated
Box 7, Folder 15
Mapping Cuts in Clones, BSTE II Digests of Deletion Mutants, Folder 1 of 2 undated
Box 7, Folder 16
Mapping Cuts in Clones, BSTE II Digests of Deletion Mutants, Folder 2 of 2 undated
Box 7, Folder 17
Mapping Cuts in Clones, Cosmid Clones undated
Box 7, Folder 18
Mapping Cuts in Clones, SMA Digests of Deletion Mutants undated
Box 7, Folder 19
Mapping Cuts in Clones, T37 Map, Raw Data, Rough Draft Maps undated
Box 7, Folder 20
Meetings 1981 Summer
Box 7, Folder 21
Michael Kahn, Construction of a Cosmic Gene Bank... Proposal 1979 October 25
Box 7, Folder 22
Northerns Graphs and Papers 1977, undated
Box 7, Folder 23
PhD Thesis Research Binder 1965-1966
Box 8, Folder 1
PhD Research, Dubnau, Gene Conservation 1965 September
Box 8, Folder 2
PhD Research Expression, Article 1958 October 3
Box 8, Folder 3
PhD Research, Fate of Donor DNA 1960-1965
Box 8, Folder 4
PhD Research, Integration - Genetics Studies 1963-1964
Box 8, Folder 5
PhD Research Uptake undated
Box 8, Folder 6
Photographs undated
Box 8, Folder 7
Plant Satellite DNA 1968-1977
Box 8, Folder 8
Plastid DNA Papers 1975-1977
Box 8, Folder 9
Recombinant DNA, Public 1976-1978
Box 8, Folder 10
Recombinant DNA Research Proposal c. 1978
Box 8, Folder 11
Renatured Mouse Satellite DNA Paper 1973
Box 8, Folder 12
Renatured Mouse Satellite DNA Paper 1973
Box 8, Folder 12
Restriction Endonucleases Purification, Methods 1976-1979
Box 8, Folder 13
Restriction Enzyme Isolation 1978
Box 8, Folder 14
Restriction Enzyme Isolation, Chilton et al., Edinburgh preprint Notes undated
Box 8, Folder 15
Restriction Enzyme Isolation, Yadav Grant Applications Notes undated
Box 8, Folder 16
Schell Preprints Reprints 1976-1978
Box 8, Folder 17
Seminar Notes 1979-1980
Half box 9, Folder 1
Simon Silver Mechanisms of Plasmid-Determined Resistance Mercury... c. 1979
Half box 9, Folder 2
Tomato 1973-1975
Half box 9, Folder 3
Translocatable Elements 1977
Half box 9, Folder 4
United States/Australia Science Foundation Grant Application 1981
Half box 9, Folder 5
University of Minnesota Symposium, Emergent Techniques for the Genetic Improvement of Crops, Notes 1979 March
Half box 9, Folder 6
Publications and Manuscripts 1965-1982
Size: 0.5 linear feet

This series includes Mary-Dell Chilton's publications in various forms, including manuscripts, preprints, and reprints. It also includes supporting records when the creator had originally included such records with the file. Thus, some research notes are contained in this series rather than in the Research series. The series includes publications written solely by Chilton as well as some publications written jointly with other scientists.

1 archival box

Agrobacterium Tumefaciens undated
Box 10, Folder 1
Agrobacterium Ti Plasmids As a Tool for Genetic Engineering in Plants 1980
Box 10, Folder 2
Bevan and Chilton Manuscript Research and Notes 1981, undated
Box 10, Folder 3
Bevan and Chilton Northern Manuscript, Multiple Transcripts of T-DNA... undated
Box 10, Folder 4
Bridgehead Dehydrohalogenation in the Photodimer of 9-chloroanthracene 1965
Box 10, Folder 5
Detection and Quantitation of Octopine in Normal Plant Tissue and in Crown Gall Tumors 1974 February
Box 10, Folder 6
DNA from Maize with and without B. Chromosomes: A Comparative Study 1973 August
Box 10, Folder 7
Fingerprints of Agrobacterium Ti Plasmids 1978
Box 10, Folder 8
Foreign DNA...is Transcribed in Crown Gall Tumors 1977 October 6
Box 10, Folder 9
Genetic and Base Sequence Homologies in Bacilli 1969 January 14
Box 10, Folder 10
Highly Conserved DNA...Overlaps T-DNA Maintained in Plant Tumors 1978 September 14
Box 10, Folder 11
Hybridization of Ribonucleic Acid with Unique Sequences of Mouse Deoxyribonucleic Acid 1972
Box 10, Folder 12
Nuclear CplMt Manuscript T-DNA from Agrobacterium Ti Plasmid... 1980
Box 10, Folder 13
On the Question of the Integration of...Bacterial DNA into Plant DNA 1975 July
Box 10, Folder 14
On the Question of Integration of...Deoxyribonucleic Acid by Tomato Plants 1975 December
Box 10, Folder 15
Restriction Endonuclease Analysis of Virulence Plasmids From Agrobacterium Tumefaciens 1978
Box 10, Folder 16
Restriction Endonuclease Mapping of a Plasmid... 1978
Box 10, Folder 17
Ribosomal DNA in a Nuclear Satellite of Tomato 1975
Box 10, Folder 18
Search for Bacterial DNA in Crown Gall Tumors 1977
Box 10, Folder 19
Short Direct Repeats Flank the T-DNA on a Nopaline T. Plasmid 1982 October
Box 10, Folder 20
Site-Specific Insertion of Genes Into T-DNA... 1981
Box 10, Folder 21
Stable Incorporation of Plasmid DNA into Higher Plant Cells 1977 June
Box 10, Folder 22
Studies of the T-DNA of Agrobacterium Ti Plasmids 1978
Box 10, Folder 23
T-DNA of a Crown Gall Teratoma is Covalently Joined to Host Plant DNA 1980 October 2
Box 10, Folder 24
Tailoring the Agrobacterium Ti Plasmid as a Vector for Plant Genetic Engineering 1981
Box 10, Folder 25
Theoretical Explanation of Mouse Satellite DNA Renaturation Kinetics 1973 November 7
Box 10, Folder 26
Transforming Activity in Both Complementary Strands of Bacillus subtilis DNA 1967 August 18
Box 10, Folder 27
Transforming Activity in Single-stranded DNA from Bacillus subtilis 1968
Box 10, Folder 28
Yadav, et al., Covalent Joining 1980
Box 10, Folder 29
Yadav, et al., Short Direct Repeats Flank the T-DNA and Supporting Research, Folder 1 of 4 1980-1982
Box 10, Folder 30
Yadav, et al., Short Direct Repeats Flank the T-DNA and Supporting Research, Folder 2 of 4 1980-1982
Box 10, Folder 31
Yadav, et al., Short Direct Repeats Flank the T-DNA and Supporting Research, Folder 3 of 4 1980-1982
Box 10, Folder 32
Yadav, et al., Short Direct Repeats Flank the T-DNA and Supporting Research, Folder 4 of 4 1980-1982
Box 10, Folder 33
Yadav, et al., Short Direct Repeats Flank the T-DNA and Supporting Research, J. Vanderleyden undated
Box 10, Folder 34
Teaching and Advising Files 1959-1999
Size: 1.25 linear feet

This series includes readings and lecture notes from courses that Mary-Dell Chilton taught in conjunction with her career in academia. It also contains several theses written by Chilton's advisees.

3 archival boxes

Bio 572, Seminar in Plant Biology, Readings #1, 9 articles 1981 Fall
Box 11, Folder 1
Bio 572, Seminar in Plant Biology, Readings #2 1981 Fall
Box 11, Folder 2
Bio 572, Seminar in Plant Biology, Readings #3-4, 8 articles 1981 Fall
Box 11, Folder 3
Bio 572, Seminar in Plant Biology, Readings #5, 4 articles 1981 Fall
Box 11, Folder 4
Bio 572, Seminar in Plant Biology, Readings #6, 5 articles 1981 Fall
Box 11, Folder 5
Bio 572, Seminar in Plant Biology, Readings #7, 6 articles 1981 Fall
Box 11, Folder 6
Biology Honors Thesis - "Construction of a pAMI-agrocin Hybrid Plasmid Using Recombinant DNA Methods," Douglas M. Brugge 1982 March 15
Box 11, Folder 7
EMBO [European Molecular Biology Organization] Course Material "The Use of Ti-Plasmid as Cloning Vector for Genetic Engineering in Plants" undated
Box 11, Folder 8
Equipment Grant for Bio 437 1981
Box 11, Folder 9
Micro 503 Lab Manual undated
Box 11, Folder 10
Micro 510 Articles, DNA Transformation 1963-1971
Box 12, Folder 1
Micro 510 Competence Lecture, Papers and Notes, Folder 1 of 3 1959-1973
Box 12, Folder 2
Micro 510 Competence Lecture, Papers and Notes, Folder 2 of 3 1959-1973
Box 12, Folder 3
Micro 510 Competence Lecture, Papers and Notes, Folder 3 of 3 1959-1973
Box 12, Folder 4
Micro 510 References, Notes, Articles 1972-1975
Box 12, Folder 5
T-Even Phage Lecture, Folder 1 of 2 1970-1971, undated
Box 12, Folder 6
T-Even Phage Lecture, Folder 2 of 2 1970-1971, undated
Box 12, Folder 7
Thesis - Excision and Transposition of Tn5 and Other Transposons, Carol Ann Egner 1981 December
Half box 13, Folder 1
Thesis - Light Modulation of PEA Fed-1 Translation Depends on its 5' End, Eric Ralph Hansen 1999
Half box 13, Folder 2
Thesis - Virulence Plasmid Found in Avirulent Mutants, Margaret Palmquest 1976 June 10
Half box 13, Folder 3
Correspondence 1963-1983
Size: 0.75 linear feet

This series includes Mary-Dell Chilton's correspondence, which is mainly professional in nature, though some contains a personal element. It also contains a small number of related records that were contained within a correspondence file by the creator.

2 archival boxes

[Armin] Braun Letters 1978
Box 14, Folder 1
Chapter for Molecular Biology of Plant Tumors 1981
Box 14, Folder 2
Chronological Labeled "Micro" 1967-1970
Box 14, Folder 3
Chronological, Outgoing Labeled "1973 Vintage" 1972-1974
Box 14, Folder 4
Crown Gall, Cucumber Satellite 1971-1972
Box 14, Folder 5
DNA Transformation, Charles Laird 1966 June 27
Box 14, Folder 6
Dubnau, D. 1967-1969
Box 14, Folder 7
Genetics Department 1963-1967
Box 14, Folder 8
[Jeff] Schell Letters 1976-1978
Box 14, Folder 10
Letters, Folder 1 of 3 1980-1983
Box 14, Folder 11
Letters, Folder 2 of 3 1980-1983
Box 14, Folder 12
Letters, Folder 3 of 3 1980-1983
Half box 15, Folder 1
[Martin] Drummond 1978
Half box 15, Folder 2
Nestor Sabbatical 1974
Half box 15, Folder 3
[R. A.] Schilperoort Letters 1978
Half box 15, Folder 4
Subject Files 1977-1981
Size: 0.5 linear feet

This series contains files maintained by Mary-Dell Chilton regarding her employment search as well as records containing information only indirectly related to her career.

1 archival box

Academic Appointment [Washington University] 1979
Box 16, Folder 1
Computer Information 1980, undated
Box 16, Folder 2
Curriculum Vitae 1978 July
Box 16, Folder 3
Departmental Seminar Program 1980-1981
Box 16, Folder 4
Diagram - Plasmids undated
Box 16, Folder 5
French Lessons and Notes 1979, undated
Box 16, Folder 6
Job Applications, Folder 1 of 2 1978
Box 16, Folder 7
Job Applications, Folder 2 of 2 1978
Box 16, Folder 8
Kotty Postle Correspondence, Grant and Fellowship Application 1977-1978
Box 16, Folder 9
Revisions of NIH [National Institute of Health] Guidelines on Experiments 1977 November 2
Box 16, Folder 10
Using the Computer 1981, undated
Box 16, Folder 11
Unprocessed Materials Undated
Unprocessed Records undated
Carton 18

Access to the collection

This collection is open for research; access requires at least 48 hours advance notice.

For more information contact us via mail, phone, or our web form.

Mailing address:
Special Collections Research Center
Box 7111
Raleigh, NC, 27695-7111

Phone: (919) 515-2273

Preferred Citation

[Identification of item], Mary-Dell Chilton Papers, MC 00376, Special Collections Research Center, North Carolina State University Libraries, Raleigh, NC

Use of these materials

The nature of the NCSU Libraries' Special Collections means that copyright or other information about restrictions may be difficult or even impossible to determine despite reasonable efforts. The NCSU Libraries claims only physical ownership of most Special Collections materials.

The materials from our collections are made available for use in research, teaching, and private study, pursuant to U.S. Copyright law. The user must assume full responsibility for any use of the materials, including but not limited to, infringement of copyright and publication rights of reproduced materials. Any materials used for academic research or otherwise should be fully credited with the source.